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Test-Category
Miscellaneous
Test-Method
colorimetric
Pack size
96 Tests
Standard concentrations included in the kit
one point calibration
Possible sample matrix and volumes
| EDTA plasma | 10 µl |
| Serum | 10 µl |
| Cell culture supernatants | 10 µl |
An overproduction of oxygen radicals or insufficient antioxidative capacity leads to a dangerous imbalance in the organism. This starts pathological mechanisms which develop several diseases. The most important disease is the cardiovascular arterosclerosis. Beside this inflammation processes, sepsis, cancerogenesis and neurodegenerative diseases are postulated.
This is the reason why the determination of the oxidative status/oxidative stress is of fundamental importance in medical diagnosis and in research. The methods used for measurement of radical-linked effects (lipid peroxidation) up to now are very time consuming (HPLC) or reflect only breakdown products of multiple unsaturated fatty acids (TBARS).
The PerOX-Assay is fast, reliable and easy to perform. Total lipidperoxides are measured. Because of a direct correlation between oxygen radicals and lipidperoxides it is possible to measure and characterize the oxidative status/oxidative stress in biological fluids.
