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Test-Category
ELISA
Pack size
96 Tests
Standard concentrations included in the kit
0.25-16 ng/ml
Possible sample matrix and volumes
| Serum | 20 µl |
| Plasma | 20 µl |
| Urine | 20 µl |
| Stool | 15 mg |
Incubation periods
Indications
Regulatory Status
EDN (eosinophil-derived neurotoxin, eosinophil protein x, EPX), a cationic glycoprotein, which is released by activated eosinophiles, has strong cytotoxic characteristics and plays a significant role in the prevention of virus infections. It is released by the eosinophile granules in places where eosinophiles are mainly found, in the skin, lungs, urogenital, gastrointestinal tract, that is, in the organs which act as an entry point for pathogens. The accumulation of EDN in the intestine is associated with tissue damage.
Measuring EDN in stool can serve as an objective parameter for a current clinical or sub-clinical cronic inflammation which is located in the gastrointestinal area. In the case of Colitis ulcerosa and Crohn's disease, the EDN measurement enables the evaluation of a disease activity and the prediction of a relapse.
