Deutsch 
Test-Category
Miscellaneous
Test-Method
photometric
Pack size
96 Tests
Standard concentrations included in the kit
one point calibration
Possible sample matrix and volumes
| Serum | 20 µl |
| Plasma | 20 µl |
| Urine | 20 µl |
| Synovia | 20 µl |
Serum protein thiol levels in blood are a direct measure of the in vivo reduction/oxidation (redox) status in humans, because thiols react readily with oxygen-containing free radicals to form disulfides. Moreover, serum thiols also reflect DNA repair capacity and the possible eventual accumulation of genetic damage, since a key DNA repair enzyme, poly ADP-ribose polymerase (PARP), is thiol/disulfide redox regulated.
Serum protein thiols can possibly be used to estimate individual aging status. Data from Banne AF et al. (2003, Anti Aging Med 6:327-34) strongly confirm an important role of oxidative stress in human disease development, and identify serum thiol status as a potential biochemical endpoint useful in the assessment of aging.
